Study on the Quality Standard for Xiao'er Hanting Granule / 中国药师
China Pharmacist
;
(12): 2074-2077, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-705430
ABSTRACT
Objective:
To establish the quality standard for Xiao'er Hanting granule.Methods:
Astragali Radix,Rhizoma Atrac-tylodis Macrocephalae (baked) and Saposhnikoviae Radix were qualitatively identified by a TLC method. The contents of calycosin-7-O-β-D-glycoside in the preparation were determined by an HPLC method. The chromatographic column was Cosmosil C18(250 mm× 4.6 mm,5 μm);the mobile phase was acetonitrile-0.2% methanoicacid(1684); the flow rate was 1.0 ml·min-1; the detection wavelength was 260 nm.Results:
Astragaloside A in Astragali Radix was detected by the TLC method,and Rhizoma Atractylodis Mac-rocephalae (baked),Saposhnikoviae Radix and saposhnkoviae standard crude drug had the same clear spots without any negative inter-ference. The linear range of calycosin- 7-O-β-D-glycoside was 0.061-0.613 μg(r =0.999 9). The average recovery was 99.4% (RSD=1.29%,n=6).Conclusion:
The method is accurate,rapid,stable and reliable with good reproducibility,which is suitable for the quality control of Xiao'er Hanting granule.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2017
Type:
Article
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