Study on Improvement of the Quality Standard for Bidouyan Granule / 中国药师
China Pharmacist
;
(12): 162-164, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-705479
ABSTRACT
Objective:
To establish the quality standard for Bidouyan granule .Methods:
Scutellariae radix and Magnoloae flos were identified by TLC.The content of baicalin was determined by HPLC with a Kromasi 1 C18 column (250 mm ×4.6 mm,5 μm). The mobile phase consisted of methanol-water-phosphoric acid (45550.2) at a flow rate of 1.0 ml· min-1, and the injection volume was 10μl.The detection wavelength was 280 nm and the column temperature was 30℃.Results:
The spots in TLC were clear without any interference.The linear range of baicalin was 10.06 μg· ml-1-100.60 μg· ml-1 (r =1.0000).The average recovery was 96.3%,and RSD was 0.7%(n=6).Conclusion:
The method is simple and specific with good repeatability , which can be used for the quality control of Bidouyan granule .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2018
Type:
Article
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