Application of Analgesic Drugs in the Pain Management after Neurosurgery / 中国药师

ABSTRACT

Analgesic treatment is an important part of perioperative management. There is no standard analgesic regimen after neurosurgery. Strong opioid receptor agonists are limited in neurosurgical patients due to miosis, respiratory depression and increased intracranial pressure. Codeine,a weak opioid receptor agonist, is the preferred regimen; however, some patients have inadequate analgesia due to metabolic differences. Tramadol,dezocine,acetaminophen,non-steroidal anti-inflammatory drugs and the other adjuvant analgesics have their own advantages and disadvantages. The clinical studies on postoperative analgesic treatment of neurosurgery were collected,analyzed and summarized in the paper. The characteristics of general and local analgesic drugs in neurosurgery were described,which could promote the rational use of analgesics.