Screening the Effective Hemostasis Fraction of Balanophora Involucrata / 中国药师
China Pharmacist
;
(12): 1098-1100, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-705675
ABSTRACT
Objective:
To screen the effective hemostasis fraction of Balanophora involucrata.Methods:
Balanophora involucrata was extracted by 95% ethanol using reflux extraction, and the residue was extracted by water. The filtrate was combined and concen-trated, and then extracted by petroleum ether, ethylacetate and n-butylalcohol in turn to respectively obtain petroleum ether phase, eth-ylacetate phase, n-butylalcohol phase and H2O phase. The effective hemostasis fraction was determined by measuring the time of blood coagulation and hemorrhage combined with plasma recalcification time.Results:
Compared with the blank group, ethylacetate extract from Balanophora involucrata could significantly shorten the time of blood coagulation and hemorrhage, and the plasma recalcification time (P<0. 01). n-Butylalcohol group at high dose could shorten the time of hemorrhage and the plasma recalcification time (P<0.05),while had no effect on the time of blood coagulation(P>0.05). Petroleum ether extract and H2O phase couldn't shorten the time of blood coagulation and hemorrhage, and the plasma recalcification time(P>0. 05).Conclusion:
The effective hemostasis frac-tion of Balanophora involucrata mainly concentrates in ethylacetate extract.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
/
Screening study
Language:
Chinese
Journal:
China Pharmacist
Year:
2018
Type:
Article
Similar
MEDLINE
...
LILACS
LIS