Determination of Calcipotriol Ointment by High-speed Counter-current Chromatography / 中国药师
China Pharmacist
;
(12): 1117-1119, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-705681
ABSTRACT
Objective:
To develop a new method for the determination of calcipotriol ointment by high-speed counter-current chro-matography(HSCCC).Methods:
An HSCCC method was used coupled with two-phase solvent system consisting of petroleum benzine-ethanol -water(2 1 0. 5, v/v/v). The injection volume was 1. 0 ml and the detection wavelength was set at 265 nm.Results:
The proposed method showed good linearity within the range of 4.02-40.20 μg·ml-1(r=0.999 4). The average recovery was 99.2%, and the RSD was 0. 4% (n=9) .Conclusion:
The HSCCC method is simple and rapid, and suitable for the determination of calcipo-triol ointment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2018
Type:
Article
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