Effect of Depressive Mood on Cellular Immunity of Inpatients in Sports Medicine Department and Humanistic Nursing Strategy / 中国医学伦理学

ABSTRACT

Objective:To investigate the influence of depressive mood of inpatients in sports medicine depart-ment on immunity and put forward nursing strategy. Methods:According to Hospital Anxiety and Depression Scale ( HADS) , the patients were divided into the depression group and non depression group, and their immune indexes were measured by flow cytometry. The immune indexes of patients between two groups were compared; Spearman correlation analysis was used to explore the relationship between depressive and immunity, and Multiple Linear Re-gression was used to analyze the effect of depressive on immunity. Results:In the 120 patients, there were 83 pa-tients showed depressive mood (69. 17％). The proportion of the NK cell and B cell in depression group was signif-icantly lower than that in the non depression group (P<0. 001). The patients' depression score was significantly negatively correlated with the proportion of NK cell and B cell ( P<0 . 001 ) . After adjusting for the socio-demo-graphic factors and disease status, depression score significantly influenced the proportion of NK cell and B cell ( P<0. 001). Conclusions:Patients' depressive mood is an influencing factor of their immunity. Nurses should pay attention to the patients' psychological condition and give them humanistic care.