DWI differential diagnosis of uterine carcinosarcoma and grade Ⅰ endometrioid adenocarcinoma / 中国医学影像技术

ABSTRACT

Objective To investigate the significance of ADC value and DWI relative signal intensity (rSI) in differential diagnosis of uterine carcinosarcoma and grade Ⅰ endometrioid adenocarcinoma (EA).Methods Totally 13 patients with uterine carcinosarcoma and 23 patients with grade Ⅰ EA which were all pathologically proved were enrolled.Conventional MRI and DWI were obtained in all 36 patients.The mean ADC values (ADC),minimum ADC values (ADCmin) and rSI were measured and compared between uterine carcinosarcoma and grade Ⅰ EA patients.Results The rSI of uterine carcinosarcoma (8.20±1.77) was significantly higher than that of grade Ⅰ EA (6.95±2.19,P=0.04).Taking rSI=7.42 as the diagnostic threshold,the area under the ROC curve was 0.71 (P＜0.05),and the sensitivity,specificity,accuracy was 69.23％,60.87％ and 61.11％,respectively.However,there was no statistical difference of ADC and ADCmin between uterine carcinosarcoma and grade Ⅰ EA patients (both P＞0.05).Conclusion ADC value is of limited significance in differential diagnosis of uterine carcinosarcoma and grade Ⅰ EA,whereas rSI is useful for the identification of these two diseases.