Diagnosis of Parotid Eosinophilic Lymphogranuloma Characterized by Multiple Nodules and Masses by Using Multi-slice Spiral CT / 中国医学影像学杂志

ABSTRACT

Purpose To explore the clinical features and multi-slice spiral CT (MSCT) imaging characteristics of nodule-type and mass-type parotid eosinophilic lymphogranuloma,in order to improve the understanding of the disease.Materials and Methods The clinical and imaging data of 6 patients with nodule-type or mass-type parotid eosinophilic lymphogranuloma confirmed by surgery pathology in Chongqing Jiulongpo Chinese Medicine Hospital from June 2007 to March 2016 (experimental group) were retrospectively analyzed.Another 32 synchronous patients with Warthin tumor confirmed by surgery pathology were enrolled as the control group.MSCT conventional and enhanced scanning were performed on all these patients,and the clinical features and MSCT characteristics were compared between the two groups.Results Compared with patients with Warthin tumor,the value and percentage of peripheral eosinophil and serum IgE level increased in all the 6 patients (age ＜ 50) with eosinophilic lymphogranuloma,and the difference was statistically significant (P＜0.01).Compared with Warthin tumor,eosinophilic lymphogranuloma was often accompanied by ipsilateral parotid enlargement,neck deep fascia thickening and edge blurring,lesions reducing,and neck lymph node enlargement.The enhanced scanning of eosinophilic lymphogranuloma showed delayed enhancement,and the enhancement in venous phase and delayed-phase was significant;while Warthin tumor showed significant enhancement in arterial phase and contrast clearing features in delayed-phase.Conclusion The MSCT findings of eosinophilic lymphogranuloma characterized by nodules or masses shows features of inflammatory lesions,in which mass density is relatively uniform and presents delayed enhancement.Combining clinical manifestation with laboratory tests will contribute to distinguish eosinophilic lymphogranuloma and Warthin tumor.