Hyponatremia and Generalized Edema Associated with Ibuprofen Therapy in a Neonate
Journal of the Korean Society of Neonatology
;
: 176-179, 2006.
Article
in Korean
| WPRIM
| ID: wpr-70640
ABSTRACT
Ibuprofen is a nonsteroidal anti-inflammatory, analgesic, and antipyretic agent which has used for the treatment of rheumatoid and musculoskeletal disorders. Its side effects have generally been minor; these include dyspepsia, anorexia, nausea and vomiting, constipation, rashes, dizziness, and tinnitus. Ibuprofen is a prostaglandin synthetase inhibitor that is not recommended for neonates. It is pharmacologically similar to indomethacin, which is used to treat symptomatic patent ductus arteriosus in premature infants. We report here a case of a term infant who developed severe hyponatremia and generalized edema associated with the ingestion of an overdose of ibuprofen. The baby made a complete recovery.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tinnitus
/
Vomiting
/
Infant, Premature
/
Anorexia
/
Ibuprofen
/
Indomethacin
/
Prostaglandin-Endoperoxide Synthases
/
Constipation
/
Dizziness
/
Ductus Arteriosus, Patent
Limits:
Humans
/
Infant
/
Infant, Newborn
Language:
Korean
Journal:
Journal of the Korean Society of Neonatology
Year:
2006
Type:
Article
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