The manifestation and analysis of MRI for primary hepatic fibrosarcoma / 中国医学装备

ABSTRACT

Objective: To investigate the characteristics of magnetic resonance imaging (MRI) for primary hepatic fibrosarcoma so as to enhance the cognition for primary hepatic fibrosarcoma. Methods: The clinical documents, laboratory data and manifestations of MRI and pathology of 1 patient with primary hepatic fibrosarcoma were researched by using retrospective analysis, and the previously relevant literatures were combined to analyze and summarize MRI imaging characteristic of primary hepatic fibrosarcoma. Results: The primary hepatic fibrosarcoma has series of characteristics included of lower incidence, wider range of age, usual occurrence in male, without hepatitis history and background of liver cirrhosis, without specificity on clinical symptoms, sign and laboratory examination, and with symptoms of stomachache and glycopenia in part of patients. And the manifestations of MRI included that liver has larger phyma, and the most of boundary of phyma were clearness, and the necrosis, cystic change and bleeding could be found in inner of phyma, and there was no calcification, and hematogenous metastasis often occurred and lymphatic metastasis was rare. The enhanced scan showed that tumor wall, tumor septa and solid component have been continuously enhanced. And the pathological manifestation of primary hepatic fibrosarcoma showed that it was spindle cell sarcoma. And the results of immunohistochemistry indicated that alpha fetoprotein (AFP) was (-), and smooth muscle actin (SMA) was (+) and vimentin was (+). Conclusion: Hepatic fibrosarcoma is rare in clinical practice, but its malignancy is pretty high and its prognosis is poor. To enhance the cognition about the characteristics of MRI about primary hepatic fibrosarcoma would contribute to correctly diagnose it.