PTC: The correlation between sonographic characteristics of ultrasound and metastasis of cervical lymph node / 中国医学装备

ABSTRACT

Objective: To analyze the correlation between sonographic characteristics of ultrasound and metastasis of cervical lymph node of papillary thyroid carcinoma (PTC). Methods: 498 patients with PTC who once received radical operation of thyroid cancer and cervical lymph node dissection were divided into metastasis group (n=163) and non-metastasis group (n=335) according to results post pathology. Gender, age, the number of lesion, maximum diameter, aspect ratio, margin, whether contacted with tunica, border, halo of ultrasound, whether existed hypoecho in interior, whether the echo was uniform, whether existed difference about some characteristics of calcification and blood flow between the two groups were compared and analyzed. The correlation of characteristics and cervical lymphatic metastasis was analyzed by using single factor analysis, and the malignancy phenomenon of ultrasonogram that was closely relevant with cervical lymph node metastasis of patients with PTC were screened out by using Logistic regression. Results: As the results of single factor analysis, there were a certain correlation between series of factors, such as gender, age, the number of lesion, maximum diameter, margin, whether contacted with tunica, blood flow and whether contained tiny calcification, and cervical lymph node metastasis, and these correlations were significant (x2=33.094, x2=126.566, x2=127.961, x2=145.087, x2=53.757, x2=6.807, P<0.05). The results of Logistic regression indicated that these factors, included multi- lesions, maximum diameter more than 10.0mm, irregular margin, contacted with tunica of thyroid and abundant blood flow, were closely correlative with the malignancy phenomenon of ultrasonogram of cervical lymphatic metastasis of patients with PTC, and their correlation coefficient were significant (OR=3.103, OR=3.595, OR=2.822, OR=6.317, OR=2.078, P<0.05). Conclusion: The characteristics of ultrasonogram contributes to increase the detectable rate of ultrasound for cervical lymph node metastasis of patients with PTC, and it can provide reference for clinical decision.