EBV-elicited familial hemophagocytic lymphohistiocytosis
Yonsei Medical Journal
;
: 245-248, 1997.
Article
in English
| WPRIM
| ID: wpr-70657
ABSTRACT
Familial hemophagocytic lymphohistiocytosis (FHL) is a rapidly fatal illness, usually encountered in infancy, characterized by fever, hepatosplenomegaly, pancytopenia, and central nervous system involvement. Microscopic examination of tissue shows a non-malignant lymphohistiocytic infiltrate, with prominent erythrophagocytosis. FHL is an autosomal recessive hereditary disorder but may develop secondarily to other conditions such as immunosuppression, malignancies, fat overload and certain infections. We recently experienced a case of siblings developing FHL, which may be associated with EBV infection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tumor Virus Infections
/
Histiocytosis, Non-Langerhans-Cell
/
Herpesvirus 4, Human
/
Herpesviridae Infections
Limits:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
English
Journal:
Yonsei Medical Journal
Year:
1997
Type:
Article
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