Relationship between left ventricular volume parameters and cardiac function in elderly patients with heart failure / 中国综合临床

ABSTRACT

Objective To explore the relationship between left ventricular volume parameters and cardiac function in elderly patients with heart failure. Methods From January 1st, 2012 to December 31st, 2014,five hundred and twenty-eight heart failure elderly patients with coronary heart disease,hypertension,heart valve disease, dilated cardiomyopathy, and hypertrophic cardiomyopathy in Kailuan General Hospital were collected in this study. The left ventricle diastolic end volume ( LVEDV ) , left ventricle end systolic volume ( LVESV) and left ventricular ejection fraction of the patients were measured. The concentrations of N type brain natriuretic peptide ( NT-proBNP ) and related biochemical indexes were detected. Results Among the 528 patients with cardiac insufficiency,367 were males and 161 were females. Among them,there were 199 cases of heart function I,163 cases of heart function II,99 cases of heart function III and 67 cases of heart function IV. Correlation analysis showed that the correlation coefficients of LVEDV, LVESV and age were 0. 431 ( P=0. 001) ,0. 472 ( P=0. 001 ) and 0. 243 ( P<0. 001 ) , respectively. Logistic regression analysis showed that LVEDV ( OR=2. 654, 95%CI 2. 124-3. 894, P=0. 004 ) , LVESV ( OR=2. 939, 95%CI 2. 539-3. 256, P=0. 001),LVESV),NT-proBNP (OR=2. 921,95%CI 2. 888-3. 562,P=0. 002) were risk factors for heart failure. Conclusion The correlation between LVESV and cardiac function in elderly patients with heart failure is better than that in LVEDV,and the correlation between the two and cardiac function is better than that of age.