Analysis of pregnancy outcomes of polycystic ovary syndrome patients after frozen embryo transfer / 中华妇产科杂志

ABSTRACT

Objective To investigate pregnancy outcomes of the patients with polycystic ovary syndrome(PCOS)after frozen embryo transfer(FET). Methods Data of 2367 PCOS patients received in vitro fertilization-embryo transfer [including fresh embryo transfer (fET) and FET] from January 2009 to December 2015 in Peking University Third Hospital were evaluated retrospectively. The basal characteristics, pregnancy complications and outcomes were analyzed, then identified the relative factors followed. Results Totally 2367 patients received in vitro fertilization-embryo transfer1106 were treated with fET, and the rest 1261 cases were treated with FET. The incidence of gestational diabetes mellitus (GDM)was lower in FET group [4.04％(51/1261) versus 6.15％(68/1106)], the difference was statistically significant (P<0.05). Singletons born after FET had higher birth weight than fET [(3406±548) versus (3360± 533) g], the difference was statistically significant (P<0.05). There was no difference of other pregnancy complications between the two groups (all P>0.05). fET was an independent risk factor for GDM (adjusted OR=1.570, 95％CI1.075-2.294). Conclusion Compared with fET, FET could decrease the risk of GDM and receive better neonatal outcomes in patients with PCOS.