Imaging features of pancreatic metastasis from clear cell renal carcinoma / 中华放射学杂志

ABSTRACT

Objective To explore the imaging diagnosis in pancreatic metastasis from clear cell renal carcinoma. Methods Twenty three patients with pancreatic metastasis from clear cell renal carcinoma confirmed by pathology were enrolled during 2007 to 2014,and their clinical sources,images and pathologic findings were reviewed. Twenty three patients underwent CT and 8 patients underwent MRI examinations. Metastatic neoplasm in pancreas were found after nephrectomy from 3 years to 17 years (average 9 years), including17 patients were diagnosed in more than 5 years after nephrectomy. Imaging features were observed.Result Metastatic neoplasms were solitary in 5 patients and multiple in 18 patients. The diameters were from 0.2 to 5.0 cm.CT plain scan demonstrated iso-density or slight hypo-density tumors with clear boundary, without calcification, and significant enhancement. MR demonstrated significantly lower signal on T1WI and high or slightly high signal on T2WI in all metastases.After contrast injection,the metastases were enhanced significantly.In 4 cases,the obstruction of the main pancreatic duct was found. Conclusions Pancreatic metastasis from clear cell renal carcinoma mostly were found in more than 5 years after nephrectomy. The images demonstrated that single or multiple tumors with clear boundary and significant enhancement in pancreas.Medical history is the key to imaging diagnosis.