A Case of Disseminated Multidrug-Resistant Tuberculosis involving the Brain / 감염과화학요법
Infection and Chemotherapy
;
: 41-46, 2016.
Article
in English
| WPRIM
| ID: wpr-70880
ABSTRACT
We report a case of a 23-year-old female immigrant from China who was diagnosed with multidrug-resistant tuberculosis affecting her lung and brain, resistant to the standard first-line therapeutics and streptomycin. She was treated with prothionamide, moxifloxacin, cycloserine, and kanamycin. However, her headache and brain lesion worsened. After the brain biopsy, the patient was confirmed with intracranial tuberculoma. Linezolid was added to intensify the treatment regimen, and steroid was added for the possibility of paradoxical response. Kanamycin was discontinued 6 months after initiation of the treatment; she was treated for 18 months with susceptible drugs and completely recovered. To our knowledge, this case is the first multidrug-resistant tuberculosis that disseminated to the brain in Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prothionamide
/
Tuberculosis, Pulmonary
/
Biopsy
/
Brain
/
Kanamycin
/
Streptomycin
/
China
/
Tuberculoma, Intracranial
/
Tuberculosis, Multidrug-Resistant
/
Tuberculosis, Central Nervous System
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Infection and Chemotherapy
Year:
2016
Type:
Article
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