Assessment of the brain function with 18F-FDG PET/CT in patients with disorders of consciousness / 中华核医学与分子影像杂志
Chinese Journal of Nuclear Medicine and Molecular Imaging
;
(6): 97-100, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-708821
ABSTRACT
Objective To evaluate the changes of brain metabolism with 18F-fluorodeoxyglucose (FDG) PET/CT in patients with disorders of consciousness (DOC).Methods This retrospective study,from January 2007 to October 2016,included 40 patients (26 males,14 females,age range17-73 years)in the vegetative state (VS),12 patients (11 males,1 female,age range25-53 years) in the minimally conscious state (MCS),and 11 patients (10 males,1 female,age range12-68 years) in the state of recovering from DOC.All patients underwent 18F-FDG PET/CT imaging.The standardized uptake value (SUV) of multiple brain areas among 3 groups of patients was calculated and compared.One-way analysis of variance was used for data analysis.Results The SUV in different encephalic regions among 3 groups were significantly different (F values6.214-13.642,all P<0.01) except for mesencephalon.Compared with MCS group,the SUV of cerebral cortex of VS group was lower (t values2.263-3.548,all P<0.05).Compared with the recovered group,the SUV of cerebral cortex and cerebellum of VS group was lower (t values1.299-5.136,all P<0.05).Compared with the recovered group,the SUV of parietal lobe,temporal lobe,occipital lobe,thalamus and cerebellum of MCS group was lower (t values1.962-2.841,all P<0.05).Conclusion 18F-FDG PET/CT may be significant in evaluating brain function of DOC patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
Language:
Chinese
Journal:
Chinese Journal of Nuclear Medicine and Molecular Imaging
Year:
2018
Type:
Article
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