18 F?FDG PET/ CT imaging contributes to the qualitative and etiological diagnosis for ascites of un?known origin in female patients / 中华核医学与分子影像杂志

ABSTRACT

Objective To evaluate the diagnostic role of 18 F-fluorodeoxyglucose (FDG) PET/ CT in female patients with ascites of unknown origin by analyzing the characteristics of PET/ CT images. Meth?ods From April 2011 to December 2016, 117 female (average age 58 years) with ascites of unknown ori-gin who underwent 18 F-FDG PET/ CT or whose ascites were found by PET/ CT were retrospectively analyzed. The causes of ascites, level of ascites metabolism in PET/ CT, diagnostic efficacy of PET/ CT for localizing primary tumor and metastasis were analyzed. Two-sample t test was used to analyze the data. Results The most common cause of female ascites was ovarian cancer, accounting for 35.0％(41/ 117). The mean stand-ardized uptake value (SUVmean ) of malignant ascites was higher than that of benign ascites (1.41±0.40 vs 0. 94±0.47; t= 3.92, P<0.05). The total detection rate of 18 F-FDG PET/ CT for primary or metastatic tumor in malignant ascites was 89.4％(93/ 104), and 75.6％(31/ 41) for malignant ascites originating from ovari-an cancer. For patients with ovarian cancer, 18 F-FDG PET/ CT clearly localized the primary tumors in 24. 4％(10/ 41) patients and metastasis in 51.2％(21/ 41) patients. Conclusions Ovarian cancer is the most common cause of female ascites. 18 F-FDG PET/ CT has a high diagnostic value for qualitative and etio-logical diagnosis for ascites of unknown origin in females.