Value of Lp (a) in risk assessment of patients with non ST-elevation acute coronary syndrome / 中华老年心脑血管病杂志

ABSTRACT

Objective To study the value of Lp (a) in risk assessment of patients with NSTE-ACS.Methods Eighty NSTE-ACS patients were divided into elderly NSTE-ACS group (n=58) and non elderly NSTE-ACS group (n=22) with 22 elderly patients with their coronary artery stenosis ＜ 50％ served as a control group.The relationship of serum Lp (a) level with Gensini score and GRACE risk score was analyzed.Results The incidence of hypertension and DM was significantly higher,the smoking history was significantly longer,the serum LDL-C and FBG level,Gensini score and GRACE risk score were significantly higher in elderly NSTE-ACS group than in control group (P＜0.05).The age was significantly older and the GRACE risk score was significantly higher in elderly NSTE-ACS group than in non elderly NSTE-ACS group (P＜0.05).The Gensini score and GRACE risk score were positively related wtih the serum Lp (a) level (r=0.494,P＜ 0.01;r=0.432,P＜0.01).Serum Lp (a) level was an independent risk factor for NSTE-ACS (P＜0.01).Conclusion Serum Lp (a) level is closely related with the severity and outcome of NSTE-ACS,indicating that serum Lp (a) level can be used as a predictor of risk assessment in NSTE-ACS patients.