Comparison of intraoperative wake-up test performed under different methods of anesthesia in pa-tients undergoing scoliosis correction / 中华麻醉学杂志

ABSTRACT

Objective To compare the intraoperative wake-up test performed under different meth-ods of anesthesia in the patients undergoing scoliosis correction. Methods Sixty American Society of An-esthesiologists physical status Ⅰ or Ⅱ patients of both sexes, aged 14-35 yr, undergoing elective scoliosis correction, were divided into dexmedetomidine-based anesthesia group (D group) and sevoflurane-based anesthesia group (S group), with 30 cases in each group. Patients were tracheally intubated after induc-tion of anesthesia. Maintenance of anesthesia was as follows remifentanil 0. 3 μg·kg-1 ·min-1 was intra-venously infused, dexmedetomidine 0. 2 μg·kg-1 ·h-1 was intravenously infused in group D, and group S inhaled low flow sevoflurane 1 L∕min with the end-tidal concentration of 0. 8％ - 1. 5％. Narcotrend index value was maintained at 30-45. The wake-up time, adverse events, requirement for vasoactive agents and blood loss during wake-up test were recorded. The wake-up quality was evaluated. Results All the pa-tients successfully completed wake-up tests. Compared with group S, the wake-up quality was significantly increased, the incidence of agitation and bucking was decreased during wake-up test, the blood loss was reduced during wake-up test (P<0. 05), and no significant change was found in wake-up time or require-ment for vasoactive agents in group D (P>0. 05). Conclusion Dexmedetomidine-based anesthesia pro-duces better efficacy for intraoperative wake-up test than sevoflurane-based anesthesia in the patients under-going scoliosis correction.