Research progress on the genes related to androgens in polycystic ovary syndrome / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 895-898, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-710022
ABSTRACT
Polycystic ovary syndrome( PCOS) is one of the most common endocrine disorders in women of reproductive age, resulting in several health complications such as menstrual dysfunction, infertility, hirsutism, acne, obesity, and metabolic syndrome. PCOS is recognized to be a complex polygene disease. Although the cause of PCOS has not been fully clarified, hyperandrogenism is one of the key pathogenesises of PCOS. In this article, we reviewed the effects of genes related to androgen biosynthesis,metabolism,reserve,action and regulation on the pathogenesis of PCOS based on the research progress in the candidate gene studies, genome wide association studies, as well as its epigenetics.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2018
Type:
Article
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