Sarcopenia and long-term prognosis of patients with chronic heart failure in patients aged 70 years and over / 中华内科杂志

ABSTRACT

To explore the association between sarcopenia (SAR) and long-term prognosis of patients with chronic heart failure (CHF) aged 70 years and over,182 CHF patients from January l,2012 to December 31,2014 were included in the present study.The patients were divided into the SAR group and the non-SAR group.The median follow-up period was 36 (3,57) months.The endpoint was any heart failure-related event (HFRE).There were significant differences in age,body mass index,hemoglobin,B-type natriuretic peptide,hypersensitive troponin T (hs-TnT),left ventricular ejection fraction (LVEF) and cardiac function class between the two groups (all P＜0.05).The Kaplan-Meier analysis showed that the survival time of the non-SAR patients was much longer than that of the SAR patients (P＜0.05).The multivariate Cox regression analysis indicated that SAR was an independent risk factor for HFRE suggesting a role of sarcopenia on long-term prognosis of patients with chronic heart failure.