Clinical effects of Pinggan Ditan Tongluo Decoction combined with routine treatment on cerebral infarction patients in the recovery period / 中成药

ABSTRACT

AIM To investigate the clinical effects of Pinggan Ditan Tongluo Decoction (Gastrodiae Rhizoma,Ramulus Uncariae cum Uncis,Acori tatarinowii Rhizoma,etc.) combined with routine treatment on patients for cerebral infarction recovery.METHODS One hundred and sixteen patients were randomly and equally divided into observation group for Pinggan Ditan Tongluo Decoction combined with routine treatment and control group for routine treatment,and the respective intervention went on for four weeks.RESULTS The observation group displayed a significantly higher general efficiency rate than the control group (91.38％ to 75.86％,P ＜0.05);significant group difference in triglyceride,total cholesterol and scores for neural function defect degree decrease with the observation group took a lead (P ＜ 0.05) although both groups yielded remarkable lowered values after the treatment (P ＜ 0.05).And the observation group demonstrated its overall superiority than the control group even if evaluated by the scores for daily living activity (P ＜ 0.05),which were significantly higher than the value prior to the administration (P ＜0.05);and the plaque area,intima-media thickness (IMT),and levels of whole high viscosity (WHV),whole low viscosity (WLV),plasma viscosity (PV) (P ＜ 0.05),which were significantly lowered after the treatment (P ＜ 0.05).No obvious adverse reactions were observed in both groups.CONCLUSION Pinggan Ditan Tongluo Decoction combined with routine treatment has significantly positive clinical effects on cerebral infarction patients in the recovery period.