Chemical constituents from Polygonum lapathifolium / 中成药

ABSTRACT

AIM To study the chemical constituents from Polygonum lapathifolium L..METHODS The ethyl acetate fraction of 80％ ethanol extract of P.lapathifolium L.was isolated and purified by silica column,Sephadex LH-20 and ODS,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Fifteen compounds were isolated and identified as 2',4'-di-hydroxy-6'-mehtoxy-chaltone (1),2',6'-di-hydroxy-4'-methoxy-chaltone (2),2',3'-di-hydroxy-4',6'-di-methoxy-chaltone (3),kaempferol (4),quercetin (5),quercetin-3-O-α-L-rhamnoside (6),quercetin-3-O-α-L-rhamnoside (7),kaempferol-3-O-α-L-rhamnoside (8),kaempferol-3-O-β-D-glucoside (9),quercetin-3-O-β-D-galactoside (10),quercetin-3-O-β-D-glucoside (11),kaempferol-3-O-β-D-galactoside (12),quercetin-3-O-(2"-O-galloyl)-rhamnoside (13),quercetin-3-O-(2"-O-galloyl)-glucoside (14),quercetin-3-O-[(6"-O-transferuloyl)-β-D-galactoside] (15).CONCLUSION Compound 3-8 are isolated from this plant for the first time.