Clinical efficacy of modified Takada procedure duodenum-preserving pancreatic head resection and pancreatoduodenectomy for the treatment of pancreatic head lesions / 中华普通外科杂志

ABSTRACT

Objective To investigate the clinical efficacy of modified Takada procedure duodenum-preserving pancreatic head resection (DPPHR) and pancreatoduodenectomy (PD) for the treatment of pancreatic head lesions.Methods 6 cases of DPPHR with the modified Takada procedure were compared with 6 cases of classical PD.The clinical data were analyzed,and the short-term prognosis was compared.Results The operation time was(281.7 ±42.6)min in DPPHR group,and(308.3 ±41.1)min in PD group (P ＜ 0.05).The intraoperative blood loss were (300 ± 187) ml in DPPHR group and (270 ± 66) ml in PD group (P ＞ 0.05).The postoperative recovery time to oral food-intake and postoperative hospital stay were (3.7 ± 1.6) days and (6.8 ± 1.7) days in DPPHR group and (9.0 ±4.3) days and(14.8 ±2.1)days in the PD group (P ＜ 0.05).The KPS scores at 3 months and 6 months after operation in DPPHR group (90.0 ± 6.2,96.7 ±5.1) were better than that of the PD group (78.0 ±7.5,90.0 ±6.3) (P ＜0.05).There was no significant difference between the two groups in the complication rate and recurrence rate in this period of time(P ＞ 0.05).Conclusion DPPHR with the modified Takada procedure is safe and effective for the treatment of pancreatic head lesions.