Dyskinesia in Parkinson's disease:risk factors, diagnosis and treatment / 中华神经科杂志
Chinese Journal of Neurology
; (12): 1002-1007, 2018.
Article
in Zh
| WPRIM
| ID: wpr-711068
Responsible library:
WPRO
ABSTRACT
Dyskinesia is one kind of motor complications caused by prolonged administration of levodopa to patients affected by Parkinson's disease. The mechanisms of dyskinesia in Parkinson's disease are still unknown. Recent research suggests the prevalence of dyskinesia mainly depends on genetic factors, levodopa therapy,clinical subtype, body weight and gender. Accumulating evidence indicates that assessment scales, functional magnetic resonance imaging and biomarkers could improve the clinical diagnosis and assessment of dyskinesia. In addition, a number of clinical trials of dyskinesia have indicated that new drugs such as an extended-release formulation of adamantine, and physical therapy such as repetitive transcranial magnetic stimulation are beneficial to the treatment of dyskinesia.
Full text:
1
Index:
WPRIM
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Language:
Zh
Journal:
Chinese Journal of Neurology
Year:
2018
Type:
Article