Advances in pertussis toxin detoxification / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
;
(12): 796-800, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-711456
ABSTRACT
Pertussis toxin (PT) is one of the major virulence factors of Borrelia pertussis and also an essential component of pertussis vaccines. Before using it in vaccine production, detoxification is necessa-ry because of its biological activity. This paper summarized the structure and detoxification process of PT as well as the safety and immunogenicity of pertussis vaccines prepared with detoxified PT.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Microbiology and Immunology
Year:
2018
Type:
Article
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