Placental growth factor: a useful predictable marker in predicting preeclampsia / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
;
(12): 879-882, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-712231
ABSTRACT
The placental growth factor ( PlGF) is a kind of glycoprotein with four isoforms , which is predominantly expressed in the placenta . The PlGF plays an important role in the angiogenesis and development , as a biomarker of placenta angiogenesis , the decreasing of the PlGF expression may lead to the dysfunction of vascularization .Anti-angiogenesis is a pathological characteristic of pre-eclampsia.The PlGF levels both in the serum and urine are lower in preeclampsia than those in normal pregnancy .Due to the decreasing of PlGF during the first trimester , the PlGF is an important predictable marker of preeclampsia .It is also expected to be used in the treatment of preeclampsia .
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Laboratory Medicine
Year:
2018
Type:
Article
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