Efficacy and safety of picosecond Alexandrite laser in treatment of nevus of Ota / 中华医学美学美容杂志

ABSTRACT

Objective To analyze the efficacy,safety and the correlative influencing factors of picosecond Alexandrite laser in the treatment of nevus of Ota.Methods 49 patients with nevus of Ota receiving picosecond Alexandrite laser in our department from October 2015 to October 2017 were retrospectively analyzed,and grouped according to patient gender,age of onset,age of first treatment,Tanino classification of skin lesions and color grading.Clinical characteristics,treatment effects,adverse reactions,influencing factors and other factors were analyzed.Results 49 patients with nevus of Ota were treated 1-4 times,and 9 cases were cured.After one treatment,the significant effective rate was 28.6 ％,the effective rate was 53.1 ％,and the effective rate was 100 ％ after 3 treatments,and the effective rate was 100％ after 4 treatments.No significant difference was found in the first treatment efficacy between different genders,age of onset,Tanino classification and color grading (P＞0.05).There was a significant difference in the first treatment effect between different first treatment age groups (P＜0.05).The inverse relationship between age and efficacy was found.The younger the age,the better the first treatment effect.Pigmentation appeared in 2 patients after treatment and subsided after 6 months.No adverse reactions such as scars and hypopigmentation appeared.Conclusions Picosecond Alexandrite laser is a safe and highly effective therapy for nevus of Ota.