Relevant factors analysis of postoperative complications in elderly patients with colorectal cancer / 肿瘤研究与临床

ABSTRACT

Objective To analyze the related factors of postoperative complications in elderly patients with colorectal cancer (≥80 years old) and to explore its prevention and treatment strategies. Methods A total of 86 patients with advanced colorectal cancer in Shanxi Dayi Hospital from January 2012 to January 2018 were selected, which were divided into the laparosopic group (35 cases) and the open group (51 cases) according to the operation methods. The clinical data, surgical methods, postoperative complications and related factors of the patients were retrospectively analyzed. Results The amount of bleeding, postoperative anal exhaust time and hospitalization time in the laparoscopic group were less than those in the open group, and the differences were statistically significant (t= 2.107, 3.631, 7.563, all P< 0.05). There was no significant difference in operative time between the laparoscopic group and the open group (t= 2.306, P>0.05). There was no significant difference in the number of postoperative complications for the patients whether cardiovascular and cerebrovascular diseases, diabetes and lung diseases were involved between the two groups (all P>0.05). The number of poor wound healing in the body mass index (BMI) ≥28 kg/m2 group (8 cases, 25.0 ％) was more than that in the BMI < 28 kg/m2 group (3 cases, 5.6 ％), and the difference was statistically significant (χ2= 5.179, P= 0.023). There was no statistical difference in the number of other complications between BMI ≥ 28 kg/m2 group and BMI < 28 kg/m2 group (all P> 0.05). The number of postoperative anastomotic fistula, pulmonary infection and poor wound healing in the laparoscopic group were all lower than those in the open group, and the differences were statistically significant (all P< 0.05). There were no statistically significant differences in postoperative cardiovascular and cerebrovascular accidents between the laparoscopic group and the open group (P= 0.543). Conclusions The elderly patients with colorectal cancer should attach great importance to perioperative diagnosis and treatment, so that preoperativecomplications can be effectively treated and controlled. Besides, it is necessary to give preference to laparoscopic surgery in the prevention of postoperative complications for elderly patients with colorectal cancer.