IgG4-related Skin Disease: Experience with Two Cases / 대한피부과학회지
Korean Journal of Dermatology
;
: 197-201, 2018.
Article
in Korean
| WPRIM
| ID: wpr-713428
ABSTRACT
IgG4-related disease (IgG4-RD) is a new disease entity characterized by elevated serum IgG4 and infiltration of IgG4+ plasma cells in tissue. IgG4-RD can involve various organs, and skin could also be affected. The manifestations of IgG4-related skin disease (IgG4-RSD) are not characteristic, however it usually presents with multiple erythematous nodules or plaques with itching sensation. We report two cases of IgG4-RSD. Histological studies of these cases revealed infiltration of numerous plasma cells and mononuclear cells in the entire dermis. Some plasma cells were strongly positive for IgG4 stain. IgG4-RSD is a treatable disease with systemic corticosteroids. Thus, clinicians should obtain a biopsy and identify IgG4-positive cells for an accurate diagnosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma Cells
/
Pruritus
/
Sensation
/
Skin
/
Skin Diseases
/
Biopsy
/
Immunoglobulin G
/
Adrenal Cortex Hormones
/
Dermis
/
Diagnosis
Type of study:
Diagnostic study
/
Prognostic study
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2018
Type:
Article
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