Your browser doesn't support javascript.
loading
The Role of B Cells in Transplantation Rejection / 대한이식학회지
The Journal of the Korean Society for Transplantation ; : 1-6, 2018.
Article in English | WPRIM | ID: wpr-713610
ABSTRACT
B cells play a role in graft rejection via several mechanisms. Specifically, B cells produce high-affinity antibodies to alloantigens including allogeneic major histocompatibility complex (MHC) with the help of follicular helper T cells. B cells also function as antigen-presenting cells for alloreactive T cells, resulting in the activation of alloreactive T cells. Conversely, the frequency of regulatory B cells increases under inflammatory conditions and suppresses the rejection process. Here, the differential roles of the major B cell subpopulations (B-1, follicular B, marginal zone B, and regulatory B cells) involved in transplantation rejection are discussed together with their interaction with T cells.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: B-Lymphocytes / T-Lymphocytes / T-Lymphocytes, Helper-Inducer / B-Lymphocytes, Regulatory / Graft Rejection / Isoantigens / Major Histocompatibility Complex / Antibodies / Antibody Diversity / Antigen-Presenting Cells Language: English Journal: The Journal of the Korean Society for Transplantation Year: 2018 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: B-Lymphocytes / T-Lymphocytes / T-Lymphocytes, Helper-Inducer / B-Lymphocytes, Regulatory / Graft Rejection / Isoantigens / Major Histocompatibility Complex / Antibodies / Antibody Diversity / Antigen-Presenting Cells Language: English Journal: The Journal of the Korean Society for Transplantation Year: 2018 Type: Article