Analytical Performance of New ARCHITECT AFP Assay: Comparison with the Current Assay
Laboratory Medicine Online
;
: 62-65, 2018.
Article
in English
| WPRIM
| ID: wpr-713886
ABSTRACT
Alpha-fetoprotein (AFP) is frequently used for hepatocellular carcinoma (HCC) diagnosis and surveillance. Although the current ARCHITECT AFP (List number 7K67) assay range is 0–350 ng/mL, all samples with test results between 200 and 350 ng/mL must be diluted and retested until their levels are <200 ng/mL. A new ARCHITECT AFP (8100/3P36) assay with a dynamic range of up to 2000 ng/mL has been introduced. The aim of this study was to perform a method comparison between the current ARCHITECT AFP assay and the new assay. The precision study showed excellent results for both high and low controls. There was a positive correlation between the two assay systems and clinical samples. The new ARCHITECT AFP assay with a wide assay range demonstrated good analytical performance. Therefore, the current ARCHITECT AFP assay could be replaced by the new assay, which is more convenient and minimizes manual labor.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Alpha-Fetoproteins
/
Carcinoma, Hepatocellular
/
Diagnosis
/
Methods
Type of study:
Diagnostic study
/
Practice guideline
Language:
English
Journal:
Laboratory Medicine Online
Year:
2018
Type:
Article
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