Optic Nerve Sheath Meningioma: Preliminary Analysis of the Role of Radiation Therapy
Brain Tumor Research and Treatment
;
: 8-12, 2018.
Article
in English
| WPRIM
| ID: wpr-714211
ABSTRACT
BACKGROUND:
The purpose of this study was to evaluate the treatment outcome of our optic nerve sheath meningioma (ONSM) case series in terms of preventing tumor growth and preserving vision in ONSM patients.METHODS:
Between July 2003 and March 2015, 1,398 patients with intracranial meningioma were diagnosed at Seoul National University Bundang Hospital. Among them, only 13 patients (0.93%) were diagnosed with ONSM and enrolled in the present study. Tumor volume changes of ONSM patients and their visual acuity were evaluated before and after treatments.RESULTS:
The median follow-up time was 50 months (range, 12–133 months). Visual acuity was evaluated in 12 of 13 patients, and visual acuity was found to be preserved in 9 of 12 patients (75%). Tumor volume was reduced in all patients. The tumor control rate was 100% in the present study. The difference in tumor volume between pretreatment and last follow-up was statistically significant (p=0.015).CONCLUSION:
Intensity-modulated radiotherapy (IMRT) and gamma knife radiosurgery (GKS) could maintain visual acuity and stabilize tumor volume in ONSM patients, suggesting that IMRT and GKS may be effective therapies for ONSM. However, which treatment is the more effective modality must be confirmed by prospective studies and longer-term follow-up.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Optic Nerve
/
Visual Acuity
/
Prospective Studies
/
Follow-Up Studies
/
Treatment Outcome
/
Radiosurgery
/
Tumor Burden
/
Radiotherapy, Intensity-Modulated
/
Seoul
/
Meningioma
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Brain Tumor Research and Treatment
Year:
2018
Type:
Article
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