Factors Influencing the Background Parenchymal Enhancement in Follow-Up Breast MRI after Adjuvant Endocrine Therapy
Investigative Magnetic Resonance Imaging
;
: 99-106, 2015.
Article
in English
| WPRIM
| ID: wpr-71457
ABSTRACT
PURPOSE:
To investigate factors influencing the evaluation of background parenchymal enhancement (BPE) at follow-up breast magnetic resonance imaging (MRI) after adjuvant endocrine therapy. MATERIALS ANDMETHODS:
One hundred twelve women with breast cancer and MRI of the contralateral unaffected breast before and after endocrine therapy were identified. Two readers in consensus performed blinded side-by-side comparison of BPE (minimal, mild, moderate, and marked) before and after therapy with categorical scales. Age, body mass index, menopausal status, treatment regimen (selective estrogen receptor modulator or aromatase inhibitor), chemotherapy, follow-up duration, BPE at baseline MRI, MRI field strength before and after therapy, and recurrence were analyzed for their influences on decreased BPE.RESULTS:
Younger age, premenopausal status, treatment with selective estrogen receptor modulator, MRI field strength, and moderate or marked baseline BPE were significantly associated with decreased BPE. In multivariate analysis, MRI field strength and baseline BPE showed a significant association.CONCLUSION:
MRI field strength and baseline BPE before and after therapy were associated with decreased BPE at post-therapy, follow-up MRI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Weights and Measures
/
Breast
/
Breast Neoplasms
/
Magnetic Resonance Imaging
/
Aromatase
/
Body Mass Index
/
Multivariate Analysis
/
Follow-Up Studies
/
Estrogen Receptor Modulators
Type of study:
Practice guideline
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Investigative Magnetic Resonance Imaging
Year:
2015
Type:
Article
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