Clinical Analysis of Drug Eruptions among Inpatients Seeking a Consultation with the Department of Dermatology / 대한피부과학회지
Korean Journal of Dermatology
;
: 314-321, 2018.
Article
in Korean
| WPRIM
| ID: wpr-715360
ABSTRACT
BACKGROUND:
Drug eruptions are common in hospitalized patients. Rapid and accurate diagnosis is essential but often difficult.OBJECTIVE:
This study defined the clinical features and causative drugs among inpatients presenting with drug eruptions.METHODS:
We retrospectively analyzed the clinical and laboratory data of inpatients who sought consultations with the Dermatology Department for a diagnosis of drug eruptions.RESULTS:
A total of 228 patients were diagnosed with drug eruptions, and this study included 139 patients. The highest incidence of drug eruptions was observed in patients in their 50s (22.3%). The most common latent period was up to 1 week (57.6%). The most common drug eruptions were exanthematous eruptions (59.7%), acneiform eruptions (10.8%), and urticaria (9.3%). The most common causative drugs were antibiotics (53.2%), followed by anticancer drugs (19.4%), and contrast media (6.5%). Laboratory abnormalities included eosinophilia (15.8%), abnormal liver function tests (7.9%), leukopenia (4.3%), an elevated serum creatinine level (2.2%), and leukocytosis (0.7%).CONCLUSION:
In descending order, the most frequent drug eruptions were exanthematous eruptions, acneiform eruptions, and urticaria, and the most common causative drugs were antibiotics, anticancer agents, and contrast media. Prompt diagnosis and discontinuation of the causative drug are important in this context. Clinicians should be aware of cutaneous adverse drug reactions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Referral and Consultation
/
Urticaria
/
Incidence
/
Retrospective Studies
/
Acneiform Eruptions
/
Drug Eruptions
/
Contrast Media
/
Creatinine
/
Dermatology
/
Diagnosis
Type of study:
Diagnostic study
/
Incidence study
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2018
Type:
Article
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