Higher Prevalence of Hypertension among Individuals with Restless Legs Syndrome: A Meta-Analysis
Psychiatry Investigation
;
: 701-709, 2018.
Article
in English
| WPRIM
| ID: wpr-715601
ABSTRACT
OBJECTIVE:
This study investigated the proposed association between restless legs syndrome (RLS) and the prevalence of hypertension.METHODS:
A meta-analysis was conducted based on searches of the PUBMED, EMBASE, Cochrane Library, and Korean electronic databases. Cohort and cross-sectional studies reporting the incidence of hypertension in individuals with RLS were included. Dichotomous data were pooled to obtain an odds ratio (OR) and 95% confidence interval (CI) for the prevalence of hypertension in individuals with RLS. The main outcome measure of the study was prevalence of hypertension in patients with RLS compared with a control group.RESULTS:
One cohort study and eight cross-sectional studies were included in the meta-analysis. Individuals with RLS had an increased prevalence of hypertension (all studies OR=1.13, 95% CI=1.04–1.23; cross-sectional studies OR=1.12, 95% CI=1.01–1.24). However, in subgroup analyses controlling for cardiovascular risk factors, such as diabetes mellitus and dyslipidemia, the differences in the prevalence of hypertension between RLS and control patients were no longer significant.CONCLUSION:
Patients with RLS may have a higher prevalence of hypertension, according to a pooled analysis, but the results remain to be confirmed in well-designed prospective studies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Restless Legs Syndrome
/
Odds Ratio
/
Incidence
/
Prevalence
/
Cross-Sectional Studies
/
Prospective Studies
/
Risk Factors
/
Cohort Studies
/
Outcome Assessment, Health Care
/
Diabetes Mellitus
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
/
Systematic reviews
Limits:
Humans
Language:
English
Journal:
Psychiatry Investigation
Year:
2018
Type:
Article
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