Downward bias of conductivity based point-of-care hemoglobin measurement compared with optical methods
Anesthesia and Pain Medicine
;
: 323-328, 2018.
Article
in English
| WPRIM
| ID: wpr-715749
ABSTRACT
BACKGROUND:
Point-of-care (POC) arterial blood gas analysis (ABGA) is widely used for checking hemoglobin (Hb) level. However, there is the tendency of downward bias of conductivity-based POC ABGA Hb measurement compared with optical methods. Authors tried to correct that bias by linear regression equation.METHODS:
We retrospectively collected a total of 86 Hb result pairs during surgeries. Hb measured by the Sysmex XE-2100 in the laboratory was set as the gold standard and was compared with that measured by the GEM Premier 3500. Data were compared using the Bland-Altman analysis, the reliability of transfusion decision was assessed using three-zone error grid. The linear regression analysis was performed to find out the relation between the Hb results of POC ABGA and those of laboratory based test.RESULTS:
The bias of the Hb measured between Sysmex XE-2100 and GEM Premier 3500 was −0.9 g/dl (P < 0.001, 95% confidence interval, −1.038 to −0.665 g/dl). The percentage error was 16.4%. According to error grid methodology, zone A, B and C encompassed 89.5%, 10.5% and 0% of data pairs. After adjusting the POC ABGA Hb values, the bias of the Hb measured by two methods was 0 g/dl (P = 0.991). The percentage error was 18.2%. The zone A, B and C encompassed 91.9%, 8.1% and 0% of data pairs.CONCLUSIONS:
Hb measurements obtained with reference to conductivity via a POC ABGA were significantly lower than those obtained via optical methods. This bias may deserve attention of anesthesiologists when POC ABGA Hb level is used as a transfusion guideline.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood Gas Analysis
/
Bias
/
Linear Models
/
Retrospective Studies
/
Point-of-Care Systems
/
Point-of-Care Testing
/
Methods
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Language:
English
Journal:
Anesthesia and Pain Medicine
Year:
2018
Type:
Article
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