Etiology and clinical feature of oral allergy syndrome in children
Allergy, Asthma & Respiratory Disease
;
: 219-224, 2018.
Article
in Korean
| WPRIM
| ID: wpr-716014
ABSTRACT
PURPOSE:
Oral allergy syndrome (OAS) is a unique allergic reaction to fresh fruits or vegetables, which is caused by cross-reactivity between foods and pollens. This study was conducted to investigate the clinical feature of OAS and relevant pollen allergens as well as the association between them in Korean children.METHODS:
This single-center study included 290 children who were sensitized to pollens at Severance Hospital, and the clinical characteristics of children with and without OAS were compared. A multicenter study included 97 children who were diagnosed with OAS at 3 hospitals between January 2008 and June 2014. The details of clinical features were collected by retrospective medical record reviews using a standardized case report form. The relevant pollen allergens were identified by skin prick tests and/or serum specific IgE levels.RESULTS:
The most commonly sensitized allergen was Japanese hop in pollen-sensitized children. Children with OAS were most commonly sensitized to birch and oak, and 12.4% of the pollen-sensitized children had OAS in the single center. The number of children who were newly diagnosed with OAS has increased over the past 7 years. The most common causative food of OAS was apple. More than 60% of patients with OAS had oral allergic reactions to multiple foods.CONCLUSION:
OAS may be relatively common in pollen-sensitized children. OAS should be considered in children with allergic disease and sensitization to pollens.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pollen
/
Skin
/
Vegetables
/
Immunoglobulin E
/
Allergens
/
Medical Records
/
Retrospective Studies
/
Betula
/
Asian People
/
Fruit
Type of study:
Etiology study
/
Observational study
/
Prognostic study
Limits:
Child
/
Humans
Language:
Korean
Journal:
Allergy, Asthma & Respiratory Disease
Year:
2018
Type:
Article
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