Organoid as a culture system for viral vaccine strains
Clinical and Experimental Vaccine Research
;
: 145-148, 2018.
Article
in English
| WPRIM
| ID: wpr-716054
ABSTRACT
Organoid is an in vitro multicellular form mimicking in vivo organ. Its similarity to human organ including cellular organization, molecular expression patterns, as well as genetic signatures enables to study the characteristics of infectious agents and host-pathogen interaction. For the features of organoid, this system also can be potentially used to cultivate currently uncultivable viruses of vaccine candidates. This paper will briefly describe problems in the current culture system for virus production and the possibility of organoid as culture system for viral vaccine and their current limitations that should be solved to meet the goal.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Virus Cultivation
/
In Vitro Techniques
/
Viral Vaccines
/
Organoids
/
Host-Pathogen Interactions
Limits:
Humans
Language:
English
Journal:
Clinical and Experimental Vaccine Research
Year:
2018
Type:
Article
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