Major Changes to the 2017 Revision of the World Health Organization Classification of Myeloproliferative Neoplasms / 대한내과학회지
Korean Journal of Medicine
;
: 351-359, 2018.
Article
in Korean
| WPRIM
| ID: wpr-716224
ABSTRACT
The World Health Organization (WHO) Classification of Tumors of Haematopoietic and Lymphoid Tissues was recently published in a revised fourth edition. The categories of myeloproliferative neoplasms (MPNs) have not significantly changed since the 2008 fourth edition of the classification; however, newly discovered mutations including CALR and CSF3R and improved characterizations and standardizations of morphological features of some entities, particularly BCR-ABL1-negative MPNs, have impacted the diagnostic criteria of disease entities, increasing the reliability and reproducibility of diagnoses. The 2017 revised edition attempts to incorporate new clinical, prognostic, morphologic, and genetic data that have emerged since the last edition. This article reviews the major changes in the classification and their rationale for MPN classification within the revised 2017 WHO system.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polycythemia Vera
/
World Health Organization
/
Global Health
/
Classification
/
Diagnosis
/
Primary Myelofibrosis
/
Thrombocythemia, Essential
/
Lymphoid Tissue
/
Myeloproliferative Disorders
Type of study:
Diagnostic study
/
Prognostic study
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2018
Type:
Article
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