Evaluation of Modified Core-Needle Biopsy in the Diagnosis of Thyroid Nodules
Korean Journal of Radiology
;
: 656-664, 2018.
Article
in English
| WPRIM
| ID: wpr-716270
ABSTRACT
OBJECTIVE:
Core needle biopsy (CNB) of the thyroid is an additional diagnostic method for non-diagnostic or indeterminate cytology samples. We sought to evaluate a new modified core biopsy technique and compare the concordance of its diagnosis with the final diagnosis of the surgically resected specimen. MATERIALS ANDMETHODS:
A retrospective analysis was conducted on 842 patients who had a thyroid CNB with or without a previous fine-needle aspiration from August 2002 to March 2015; 38% of patients ultimately underwent thyroidectomy. We divided the patients into two groups for comparison conventional group (n = 329) and new modified technique group (n = 513) that enabled sampling of not only the lesion but also the margin and surrounding parenchyma. The diagnostic conclusiveness of CNB and concordant rate with thyroidectomy was compared between the two groups.RESULTS:
The overall diagnostic conclusiveness did not exhibit a significant increase (77% in the conventional technique group and 75% in the modified technique group, p = 0.408). In terms of the diagnostic concordance rate between CNB and thyroidectomy, no overall significant increase was observed (83% in the conventional technique group and 88% in the modified technique group, p = 0.194). However, only in follicular-patterned lesions (nodular hyperplasia, follicular neoplasm, and follicular variant of papillary thyroid carcinoma), a significant increase in the diagnostic concordance rate was observed (83% in the conventional group and 94% in the modified technique group, p = 0.033).CONCLUSION:
Modified CNB technique can be beneficial for the accurate diagnosis of follicular-patterned thyroid lesions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thyroid Gland
/
Thyroidectomy
/
Biopsy
/
Retrospective Studies
/
Thyroid Nodule
/
Biopsy, Fine-Needle
/
Diagnosis
/
Biopsy, Large-Core Needle
/
Hyperplasia
/
Methods
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
Language:
English
Journal:
Korean Journal of Radiology
Year:
2018
Type:
Article
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