Clinical significance of Th17 cells in kidney transplantation
The Korean Journal of Internal Medicine
;
: 860-866, 2018.
Article
in English
| WPRIM
| ID: wpr-716638
ABSTRACT
Transplantation research has focused on cytotoxic T-cell and plasma cell/B-cell-targeted strategies, but little attention has been paid to the role of T helper 17 (Th17) cells in allograft dysfunction. However, accumulating evidence suggests that Th17 cells contribute to the development of acute and chronic allograft injury after transplantation of various organs, including the kidney. This review summarizes recent reports on the role of Th17 cells in kidney transplantation. Means of improving allograft outcomes by targeting the Th17 pathway are also suggested.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma
/
T-Lymphocytes
/
Kidney Transplantation
/
Th17 Cells
/
Allografts
/
Kidney
Language:
English
Journal:
The Korean Journal of Internal Medicine
Year:
2018
Type:
Article
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