The effect of tamoxifen therapy on the endometrium and ovarian cyst formation in patients with breast cancer
Obstetrics & Gynecology Science
;
: 615-620, 2018.
Article
in English
| WPRIM
| ID: wpr-716660
ABSTRACT
OBJECTIVE:
To evaluate the effect of tamoxifen on female reproductive organs in women with breast cancer.METHODS:
We retrospectively reviewed the medical records of 309 women with breast cancer who were currently receiving tamoxifen and undergoing regular gynecological examination.RESULTS:
We evaluated 92 pre- and 217 postmenopausal women. The prevalence of endometrial thickening was 12% in the pre- and 10.6% in the postmenopausal group. An endometrial biopsy was performed in 43 women and confirmed endometrial cancer in 1, endometrial polyps in 14, and endometrial hyperplasia in 4 women. Transvaginal ultrasonography showed 25 cases of newly developed ovarian cysts. Most ovarian cysts had disappeared during follow-up.CONCLUSION:
Tamoxifen use in women with breast cancer causes few complications and is considered safe for female reproductive organs in case of regular gynecological examination.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovarian Cysts
/
Ovary
/
Polyps
/
Tamoxifen
/
Biopsy
/
Breast
/
Breast Neoplasms
/
Medical Records
/
Prevalence
/
Retrospective Studies
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Obstetrics & Gynecology Science
Year:
2018
Type:
Article
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