Factors Associated with Resolution of Hypertension after Adrenalectomy in Patients with Primary Aldosteronism
Endocrinology and Metabolism
;
: 355-363, 2018.
Article
in English
| WPRIM
| ID: wpr-716969
ABSTRACT
BACKGROUND:
The aim of this study was to investigate the factors associated with resolution of hypertension after adrenalectomy in patients with primary aldosteronism. A secondary aim was to describe our use of the contralateral ratio in adrenal venous sampling (AVS) in the setting of suboptimal successful cannulation rates.METHODS:
A retrospective review of patients who underwent AVS followed by unilateral adrenalectomy for primary aldosteronism was performed.RESULTS:
Complete resolution of hypertension and hypokalemia was seen in 17 of 40 patients (42.5%), while a clinical improvement in hypertension was seen in 38 of 40 (95%). Shorter duration of hypertension, mean aldosteronoma resolution score (ARS), and a high ARS of 3 to 5 were associated with resolution of hypertension after adrenalectomy (P=0.02, P=0.02, and P=0.004, respectively). Of the individual components of ARS, only a duration of hypertension of ≤6 years was associated with resolution of hypertension after adrenalectomy (P=0.03).CONCLUSION:
A shorter duration of hypertension was significantly associated with resolution of hypertension after adrenalectomy in patients with primary aldosteronism.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Catheterization
/
Retrospective Studies
/
Adrenalectomy
/
Hyperaldosteronism
/
Hypertension
/
Hypokalemia
Type of study:
Observational study
Limits:
Humans
Language:
English
Journal:
Endocrinology and Metabolism
Year:
2018
Type:
Article
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