Association between Serum Uric Acid and Oxidative Stress in Korean Adults / 가정의학회지
Korean Journal of Family Medicine
;
: 295-299, 2018.
Article
in English
| WPRIM
| ID: wpr-717107
ABSTRACT
BACKGROUND:
Oxidative stress is implicated in the pathogenesis and development of lifestyle-related diseases. In the present study, we evaluated the correlation between the serum uric acid (UA) levels and oxidative status in Korean adults.METHODS:
The subjects were 5,093 individuals (2,041 women and 3,052 men) who underwent a health checkup between June 2012 and December 2016. Oxidative stress levels (derivatives of reactive oxygen metabolites [d-ROMs]) and antioxidant potential (biological antioxidant potential [BAP]) were measured. Metabolic markers, including UA, were also examined.RESULTS:
Higher serum UA levels were associated with decreased levels of d-ROMs (P < 0.05). The UA levels were positively associated with BAP levels (P < 0.001).CONCLUSION:
Serum UA is related to oxidative status, especially antioxidant capacity, in Korean adults; UA may play a role in antioxidant defense systems in humans.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygen
/
Uric Acid
/
Reactive Oxygen Species
/
Oxidative Stress
/
Antioxidants
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Korean Journal of Family Medicine
Year:
2018
Type:
Article
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