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A review of biocompatibility of zirconia: In vitro experiment / 대한치과보철학회지
The Journal of Korean Academy of Prosthodontics ; : 391-395, 2018.
Article in Korean | WPRIM | ID: wpr-717287
ABSTRACT
Increasing demands for zirconia material in clinics, assessment of biocompatibility of zirconia is essential. In this article, a review of in vitro studies of zirconia compatibility was performed. Zirconia showed great biocompatibility at in vitro studies with various cell lines such as fibroblasts, osteoblasts, and lymphocytes. Many studies reported that zirconia caused no cytotoxicity or mutation. Zirconia also showed less bacterial adhesion. There were no adverse effects except for small reduced strength with in vitro study mimicking long-term exposure of body fluid. According to the study with ostoblast-like cells, zirconia could regulate genes of immunity, molecular transport, and cell cycle. Such gene regulating was considered as one of the reasons of zirconia biocompatibility. With biocompatibility of zirconia powders, in vitro studies had controversial conclusions. It seems that zirconia powders might have cytotoxicity
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoblasts / Powders / Body Fluids / In Vitro Techniques / Bacterial Adhesion / Lymphocytes / Cell Cycle / Cell Line / Fibroblasts Language: Korean Journal: The Journal of Korean Academy of Prosthodontics Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoblasts / Powders / Body Fluids / In Vitro Techniques / Bacterial Adhesion / Lymphocytes / Cell Cycle / Cell Line / Fibroblasts Language: Korean Journal: The Journal of Korean Academy of Prosthodontics Year: 2018 Type: Article