The Necessity of the Simple Tests for Diabetic Peripheral Neuropathy in Type 2 Diabetes Mellitus Patients without Neuropathic Symptoms in Clinical Practice
Diabetes & Metabolism Journal
;
: 442-446, 2018.
Article
in English
| WPRIM
| ID: wpr-717357
ABSTRACT
Early recognition and appropriate management of diabetic peripheral polyneuropathy (DPNP) is important. We evaluated the necessity of simple, non-invasive tests for DPNP detection in clinical practice. We enrolled 136 randomly-chosen patients with type 2 diabetes mellitus and examined them with the 10-g Semmes-Weinstein monofilament examination, the 128-Hz tuning-fork, ankle-reflex, and pinprick tests; the Total Symptom Score and the 15-item self-administered questionnaire of the Michigan Neuropathy Screening Instrument. Among 136 patients, 48 had subjective neuropathic symptoms and 88 did not. The abnormal-response rates varied depending on the methods used according to the presence of subjective neuropathic symptoms (18.8% vs. 5.7%, P < 0.05; 58.3% vs. 28.4%, P < 0.005; 81.3% vs. 54.5%, P < 0.005; 12.5% vs. 5.7%, P=0.195; 41.7% vs. 2.3%, P < 0.001; and 77.1% vs. 9.1%, P < 0.001; respectively). The largest abnormal response was derived by combining all methods. Moreover, these tests should be implemented more extensively in diabetic patients without neuropathic symptoms to detect DPNP early.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polyneuropathies
/
Mass Screening
/
Michigan
/
Surveys and Questionnaires
/
Peripheral Nervous System Diseases
/
Diabetes Mellitus
/
Diabetes Mellitus, Type 2
/
Diabetic Neuropathies
/
Diagnosis
/
Neurologic Examination
Type of study:
Diagnostic study
/
Prognostic study
/
Screening study
Limits:
Humans
Country/Region as subject:
North America
Language:
English
Journal:
Diabetes & Metabolism Journal
Year:
2018
Type:
Article
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