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Colorectal Cancer in Young Adults
Journal of the Korean Surgical Society ; : 100-109, 1998.
Article in Korean | WPRIM | ID: wpr-71750
ABSTRACT
Colorectal cancer(CRC) is the most common gastrointestinal malignancy in the Western world. The total number of CRC cases in Korea is increasing probably due to western-style diets. CRC is relatively uncommon in the young adult group. Nevertheless, these cases warrant special attention because they are often diagnosed in an advanced stage and are more likely to involve a family history of CRC. Controversies still exist over the determination of the age range and over the true value of age factor in the prognosis for the young adults. The aim of this study is to calculate the incidence, to evaluate the clinicopathologic characteristics and the outcome of management of young adult with CRC. A retrospective review of 864 patients with an adenocarcinoma of the colon or rectum, who were surgically treated and followed-up in our Department of the Kang Buk Samsung Hospital, Sung Kwun Kwan University College of Medicine, Seoul, Korea, between January 1970 and December 1995 was performed. Among these patients, 138 were in the young adult group, aged less than 40. All cases accompanied by familial adenomatous polyposis coli and ulcerative colitis were excluded. Young adults accounted for 16.0% of all patients with CRC, showing no significant sex difference compared with the control group. The rectum and sigmoid colon were the most frequent sites of the lesion (80.4%). The incidences of Dukes' stage C and poorly differenciated adenocarcinoma cases were significantly higher in the young adult group (p<0.05). The curative resection rate of tumors in young patients was 93.4%. Despite of the more advanced stage and poorly differenciation, the stage-related and overall 5-year survival rate was not significantly different between old and young patients (57.9% and 59.4% in young and old patients, respectively). CRC in young adults in Korea is increasing in number, but its proportion is decreasing. The results of our study indicate that the prognosis and the stage-related survival for CRC in young adults are not related to age.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Rectum / Colon, Sigmoid / Colorectal Neoplasms / Adenocarcinoma / Colitis, Ulcerative / Incidence / Survival Rate / Retrospective Studies / Age Factors Type of study: Incidence study / Observational study / Prognostic study Limits: Humans Country/Region as subject: Asia Language: Korean Journal: Journal of the Korean Surgical Society Year: 1998 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Rectum / Colon, Sigmoid / Colorectal Neoplasms / Adenocarcinoma / Colitis, Ulcerative / Incidence / Survival Rate / Retrospective Studies / Age Factors Type of study: Incidence study / Observational study / Prognostic study Limits: Humans Country/Region as subject: Asia Language: Korean Journal: Journal of the Korean Surgical Society Year: 1998 Type: Article