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Injectable Biomaterials in Plastic and Reconstructive Surgery: A Review of the Current Status
Tissue Engineering and Regenerative Medicine ; (6): 559-574, 2018.
Article in English | WPRIM | ID: wpr-717545
ABSTRACT

BACKGROUND:

Injectable biomaterials have attracted increasing attention for volume restoration and tissue regeneration. The main aim of this review is to discuss the current status of the injectable biomaterials for correction of tissue defects in plastic and reconstructive surgery.

METHODS:

Requirements of injectable biomaterials, mechanism of in situ gelation, characteristics, and the combinational usage of adipose-derived stem cells (ADSCs) and growth factors were reviewed.

RESULTS:

The ideal injectable biomaterials should be biocompatible, non-toxic, easy to use, and cost-effective. Additionally, it should possess adequate mechanical properties and stability. In situ gelation method includes physical, chemical, enzymatic and photo-initiated methods. Natural and synthetic biomaterials carry their pros and cons due to their inherent properties. The combined use of ADSCs and growth factors provides enhanced potential for adipose tissue regeneration.

CONCLUSION:

The usage of injectable biomaterials has been increasing for the tissue restoration and regeneration. The future of incorporating ADSCs and growth factors into the injectable biomaterials is promising.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Plastics / Regeneration / Stem Cells / Biocompatible Materials / Adipose Tissue / Intercellular Signaling Peptides and Proteins / Methods Language: English Journal: Tissue Engineering and Regenerative Medicine Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Plastics / Regeneration / Stem Cells / Biocompatible Materials / Adipose Tissue / Intercellular Signaling Peptides and Proteins / Methods Language: English Journal: Tissue Engineering and Regenerative Medicine Year: 2018 Type: Article